IMPORTANT: We currently have a number of bugs related to image cropping and are actively trying to resolve them. In the meantime, we have disabled cropping. Apologies for any inconvenience. Stay informed: radiopaedia.org/chat

Gastrointestinal stromal tumor (GIST) of the stomach

Case contributed by Achoki Daniel
Diagnosis certain

Presentation

Presented with dizziness. On further laboratory work-up was found to have iron deficiency anemia.

Patient Data

Age: 70 years
Gender: Male

Axial non'contrast images show a well demarcated rounded fungating soft tissue mass arising from the wall of the gastric fundus. It measures 5.14 x 5.16 x 6.52 cm (anteroposterior x mediolateral x craniocaudal).

The lesion has a deep crescent shaped ulceration.

It shows subtle heterogeneous enhancement on post-IV contrast administration.

No evidence of metastases seen.

Esophagogastroduodenoscopy showed a large ulcerated sessile mass in the fundus and cardia. No active bleeding at the time. The rest of the stomach was normal. Biopsy was done.

Gastric biopsy showed a submucosal benign mesodermal tumor consisting of haphazardly interlacing spindle cells in a hyalinized stroma. The spindle cells showed no atypia or mitotic activity. CD117/CD34IHC stained positive. The final diagnosis was Gastrointestinal Stromal Tumor (Benign)

Case Discussion

Histologically confirmed GIST projecting into the lumen of the stomach. GISTs are usually found in the stomach or small intestine. Our patient presented with symptoms of upper GI bleeding. He was 70 years old, consistent with the fact that GISTs usually occur after the age of 40 with most seen in older patients.

How to use cases

You can use Radiopaedia cases in a variety of ways to help you learn and teach.

Creating your own cases is easy.

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.