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Granulomatosis with polyangiitis

Case contributed by Maxim Stalkov
Diagnosis almost certain

Presentation

Cough, hemoptysis, chest pain and fever.

Patient Data

Age: 60
Gender: Male

Bilateral cavitating masses with thick walls and multiple irregularly marginated nodules. Right-sided pleural effusion.

Case Discussion

Patient also had maxillary sinusitis and renal impairment. Findings are consistent with Wegener's granulomatosis (granulomatosis with polyangiitis). Diagnosis was verified.

The classic Wegener's triad represents involvement of upper respiratory tract, lungs and kidneys. Lungs are the most frequently involved site in granulomatosis with polyangiitis (95% of cases). 

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