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Infantile hepatic hemangioma

Case contributed by Akash Ramteke , 8 Jan 2018
Diagnosis almost certain
Changed by Henry Knipe, 3 Jun 2018

Updates to Case Attributes

Status changed from pending review to published (public).
Published At was set to .
Diagnostic Certainty was set to .
Age changed from 21 Days to 21 days.
Presentation was changed:
c/o massMass in right hypochondrium since birth.
Body was changed:

InfantileThis is a case of histopathological proven infantile hepatic hemangioma, which is a neoplasm of liver caused by the proliferation of  endothelial cell endothelial cells. It shows rapid growth in early stages and spontaneous involution.

The term “infantile hepatic hemangioma” is used instead of “hemangioendothelioma” because the clinical and biologicclinicobiologic behavior is similar to infantile hemangiomas that affect the other parts of the body.

The lesion is composed predominately of endothelial cells.

It shows rapid growth in early stages and  spontaneous involution . 

occur elsewhere. It differs from adult epithelioid hemangioendothelioma in that it has malignant potential and does not involute.

 ItIt produces symptoms such as fetal cardiovascular compromise, hydrops fetalis, hepatomegaly, haemolytic anaemia, thrombocytopenia, and  unexplainedunexplained congestive cardiac failure.

Therapeutic options include steroids, embolization, chemotherapy, radiotherapy, surgery, or liver transplantation. 

  • -<p>Infantile hepatic hemangioma is a neoplasm of liver caused by proliferation of  endothelial cell .</p><p>The term “infantile hepatic hemangioma” is used instead of “hemangioendothelioma” because the clinical and biologic behavior is similar to infantile hemangiomas that affect the other parts of the body.</p><p>The lesion is composed predominately of endothelial cells.</p><p>It shows rapid growth in early stages and  spontaneous involution . </p><p>It differs from adult epithelioid hemangioendothelioma in that it has malignant potential and does not involute.</p><p> It produces symptoms such as fetal cardiovascular compromise, hydrops fetalis, hepatomegaly , haemolytic anaemia, thrombocytopenia, and  unexplained congestive cardiac failure.</p><p>Therapeutic options include steroids , embolization , chemotherapy, radiotherapy, surgery, or liver transplantation. </p>
  • +<p>This is a case of histopathological proven infantile hepatic hemangioma, which is a neoplasm of liver caused by the proliferation of endothelial cells. It shows rapid growth in early stages and spontaneous involution.</p><p>The term “infantile hepatic hemangioma” is used instead of “hemangioendothelioma” because the clinicobiologic behavior is similar to infantile hemangiomas that occur elsewhere. It differs from adult epithelioid hemangioendothelioma in that it has malignant potential and does not involute.</p><p>It produces symptoms such as fetal cardiovascular compromise, hydrops fetalis, hepatomegaly, haemolytic anaemia, thrombocytopenia, and unexplained congestive cardiac failure.</p><p>Therapeutic options include steroids, embolization, chemotherapy, radiotherapy, surgery, or liver transplantation. </p>

Systems changed:

  • Paediatrics

Updates to Study Attributes

Findings was changed:

A large mass lesion is seen in the left lobe of liver, which shows peripheral hyperenhancement on arterial phase and gradual filling in on venous and delayed phase.

3D MIP images showsshow the characteristic reduction in the aortic diameter below the level of coeliac origin, because of the  vascularvascular redistribution toward the liver by this large hypervascular mass. This cause coeliac trunk and hepatic artery hypertrophy.

Above findings are consistent with Infantile hepatic haemangiomhaemangiomaa

This was further confirmed on histopathology.

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