Revision 11 for 'Infantile hepatic hemangioma'

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Infantile hepatic hemangioma

Infantile hepatic hemangioma is a neoplasm of liver caused by proliferation of  endothelial cell .

The term “infantile hepatic hemangioma” is used instead of “hemangioendothelioma” because the clinical and biologic behavior is similar to infantile hemangiomas that affect the other parts of the body.

The lesion is composed predominately of endothelial cells.

It shows rapid growth in early stages and  spontaneous involution . 

It differs from adult epithelioid hemangioendothelioma in that it has malignant potential and does not involute.

 It produces symptoms such as fetal cardiovascular compromise, hydrops fetalis, hepatomegaly , hemolytic anemia, thrombocytopenia, and  unexplained congestive cardiac failure.

Therapeutic options include steroids , embolization , chemotherapy, radiotherapy, surgery, or liver transplantation. 

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