Presentation
Diabetes insipidus, cough, fever, shortness of breath.
Patient Data
Age: 20 years
Gender: Male
From the case:
Langerhans cell histiocytosis
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Lytic defect of the parietal, frontal and maxillary bones in the skull.
From the case:
Langerhans cell histiocytosis
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Conventional CT reveals multiple small nodules and thin-walled, irregular cysts predominantly in the upper 1/3 of the lungs.
Case Discussion
Langerhans cell histiocytosis. The hand-Schüller-Christian disease is the chronic disseminated form, multifocal.
Other lytic lesions are identified in the femur (no image).
Etiology: Uncertain; Inflammatory ~ neoplastic
Epidemiology: Affects 4 per 1 million
Gender: M:F = 2:1
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