Left trigeminal neuralgia due to vascular compression

Case contributed by Badis Al Harbawi
Diagnosis almost certain

Presentation

Attacks of left facial pain and numbness

Patient Data

Age: 55 years
Gender: Female

There is compression of the root-entry zone of the left trigeminal nerve by the left superior cerebellar artery. Otherwise, the trigeminal nerves are normal in caliber and signal intensity.

Normal right trigeminal nerve. No posterior fossa or Meckel's cave masses. No evidence of demyelination, brain stem lesions or infarction. 

Case Discussion

Compression of the trigeminal nerve by the superior cerebellar artery is the most common cause of trigeminal neuralgia (about 90 %), followed by compression by anterior inferior cerebellar artery and basilar artery.

It is believed that only compression at root-entry zone and proximal cisternal part of the nerve where the nerve is covered by central myelin derived from oligodendrocytes is responsible for trigeminal neuralgia due to vascular compression, while the distal peripherally myelinated (Schwann cells) nerve is not responsible for this entity.

Other causes of trigeminal neuralgia include multiple sclerosis, CP angle masses or cysts and perineural spread of tumors. 

Most cases of trigeminal neuralgia are unilateral with right side affected more commonly.

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