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Lissencephaly type I

Case contributed by Frank Gaillard
Diagnosis almost certain

Presentation

Hypotonia and seizures.

Patient Data

Age: 3 months
Gender: Female

Note: This case has been tagged as "legacy" as it no longer meets image preparation and/or other case publication guidelines.

Brain

mri

There is diffuse abnormality of the overlying supratentorial mantle with a reduction in the number of gyri and marked thickening of the cortex, best seen anteriorly. 

Case Discussion

This case illustrates features typical of type I lissencephaly. 

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