Malignant spinal cord compression from glioblastoma drop metastasis

Case contributed by Roberto Schubert
Diagnosis certain

Presentation

Severe back pain and gait disturbances in a patient who had been treated for cerebral glioblastoma multiforme 12 months earlier.

Patient Data

Age: 70
Gender: Female

There is a large intradural mass at the T3 level right to the spinal cord. The cord is displaced to the left and severely compressed. The mass is hyperintense on T2 and iso- to hypointense on T1 and enhances avidly. The T2-weighted images show extensive intramedullary edema reaching from C4-T6. The contrast-enhanced images show a large intramedullary portion of the tumor.

Case Discussion

Remote metastases in GBM may also spread along the vascular system but leptomeningeal drop metastases have been more freqently described in the literature1.

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