IMPORTANT: We currently have a number of bugs related to image cropping and are actively trying to resolve them. In the meantime, we have disabled cropping. Apologies for any inconvenience. Stay informed: radiopaedia.org/chat

Medullary nephrocalcinosis (histology)

Case contributed by Andrew Ryan
Diagnosis certain

Presentation

Nephrectomy for RCC, mild pre-op renal impairment

Patient Data

Age: 40 years
Gender: Male

Histo - nephrectomy specimen

pathology

These images demonstrate extensive calcification of the stromal tissue of the medulla/renal papilla. 

Low power histological image of medullary rays (empty tubules radiating from the left of picture) extending into a renal papilla that projects into a minor calyx. The extent of the 'dark purple' areas of calcification in the medulla/papilla is well demonstrated at this level of magnification. 

High power histological image of the tip of the renal papilla (upper) including the intertubular calcification (dark purple). The intact residual medullary rays are partly atrophic. The image also demonstrates the lining urothelium of the minor renal calyx

pathology

Normal renal papillae for comparison (not from this patient).

How to use cases

You can use Radiopaedia cases in a variety of ways to help you learn and teach.

Creating your own cases is easy.

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.