Metachromatic leukodystrophy (infantile type)
Two year old child with neuronal regression
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Diffuse confluent periventricular and deep white matter increased T2 signal intensities with sparing of subcortical U fibers, predominantly in the bilateral parietal region. Linear hypointense signals also noted in the white matter giving tigroid appearance.
- Cheon JE, Kim IO, Hwang YS et-al. Leukodystrophy in children: a pictorial review of MR imaging features. Radiographics. 22 (3): 461-76. Radiographics (full text) - Pubmed citation