Metastatic insulinoma

Case contributed by Maxime St-Amant
Diagnosis certain

Presentation

Hyperinsulinism.

Patient Data

Age: 35 years
Gender: Female
ct

CT-scans shows a subtle hypervascular pancreatic lesion located at the junction of the body and tail of the pancreas, compatible with a neuroendocrine pancreatic tumor (pancreatic islet cell tumor).

Moreover, there are multiple liver lesions and pelvic carcinomatous nodules, indistinguishable from the ovaries.

Nuclear medicine

Octreoscan (somatostatin receptor scintigraphy) done one month later shows excessive somatostatin receptor expression in the liver and pancreas, compatible with a metastatic neuroendocrine tumor of pancreatic origin. There was a significant progression in this one month period follow-up.

mri

MRI done two months later shows an important progression of liver metastases. The pancreatic lesions has grown and it shows heterogeneous enhancement following gadolinium administration. Pelvic carcinomatosis is not seen on this MRI.

Case Discussion

There aren't many hypervascular pancreatic lesions except endocrine tumors of the pancreas. Apart from purely vascular lesions (aneurysm / pseudo-aneurysm), which should be easily identified on C+ studies, hypervascular metastases are amongst the only true differential diagnosis.

Related article:

How to use cases

You can use Radiopaedia cases in a variety of ways to help you learn and teach.

Creating your own cases is easy.

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.