Patient Data
Age: 10 months
Gender: Female
From the case:
Osteogenesis imperfecta and bisphosphonate lines
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Osteopaenic, gracile bones with zebra stripes. Evidence of prior right femoral fracture.
Zebra stripes from cyclical bisphosphonate therapy.
Lateral x-ray of the skull shows wormian bones.
Case Discussion
Baby girl with type II osteogenesis imperfecta, treated with cyclical bisphosphonate therapy (pamidronate) resulting in the "zebra stripe sign". Also note the wormian bones on the skull x-ray.
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