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​Papillary thyroid carcinoma

Case contributed by Frank Gaillard
Diagnosis certain

Presentation

Painless neck swelling in region of thyroid.

Patient Data

Age: 35 years
Gender: Female

Note: This case has been tagged as "legacy" as it no longer meets image preparation and/or other case publication guidelines.

Multiple thyroid nodules with heterogeneous enhancement. A necrotic node is seen at right jugular chain (level IV).

Case Discussion

FNA Final Diagnosis: 
​Papillary carcinoma of thyroid 

Microscopic Description: 
The fine needle aspirate from the neck region is a cellular aspirate showing clusters of atypical follicular epithelial cells and inspissated colloid. Some of the clusters are associated with colloid. No definite papillary fragments are seen. However, there is an occasional stromal fibrovascular core identified. Individual clusters of epithelial cells show cells with irregular nuclear outlines and nuclear grooves. A focal intranuclear inclusion is seen. There is crowding and overlapping of nuclei present. Some of the clusters have a Hurthle cell appearance with more abundant cytoplasm.

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