Primary splenic lymphoma (marginal zone lymphoma)

Case contributed by Dr Roberto Schubert


Upper left abdominal pain. Splenomegaly first detected on ultrasound.

Patient Data

Age: 50
Gender: Female


Splenic diameter about 20 cm in the long axis. Subhepatic enlarged lymph nodes.


CT Abdomen and pelvis (selected images)

Massive enlargement of the spleen with slightly inhomogeneous parenchymal enhancement. Multple enlarged lymph nodes around the celiac trunk, the hepatoduodenal ligament and the inferior vena cava. Thoracic and pelvic nodes were not involved (not shown).

Case Discussion

Splenic marginal zone lymphoma is a rare, indolent subtype of non-Hodgkin lymphoma, which accounts for less than 2%. Dull abdominal pain from splenomegaly is often the only symptom 1.
Biopsy-proven case.

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Case information

rID: 18105
Published: 8th Jun 2012
Last edited: 14th Aug 2019
Inclusion in quiz mode: Included

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