Rathke's cleft cyst: claw sign

Case contributed by Dr Amro Omar



Patient Data

Age: 44
Gender: Male

Non enhancing cystic sellar mass with hypointense non enhancing hypointense intracystic nodule and claw sign in post contrast study

Incidental finding of chronic sphenoid sinusitis


Note the "Claw" sign = enhancing rim of compressed pituitary surrounding nonenhancing cyst

Case Discussion

"Claw" sign = enhancing rim of compressed pituitary surrounding non-enhancing cyst.

Rathke cleft cyst is a nonneoplastic cyst arising from remnants of embryonic Rathke cleft

Top differential diagnoses:

  • Craniopharyngioma

  • Cystic pituitary adenoma

  • Other nonneoplastic cyst

The Claw sign has also been used in radiological literature with respect to Wilms tumor.

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Case information

rID: 32787
Published: 14th Dec 2014
Last edited: 14th Aug 2019
Inclusion in quiz mode: Included

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