Secondary hemochromatosis

Case contributed by Dr Vikas Shah


CT to characterise adrenal lesion found on imaging elsewhere


Lipid rich left adrenal adenoma.

High density throughout liver.

Normal spleen.


Lipid rich left adrenal adenoma.

Diffuse low signal throughout liver and spleen.

Case Discussion

This patient had frequent blood transfusions due to underlying myelofibrosis. In secondary hemochromatosis, there is iron overload involving the liver and spleen, with a reduction in the signal intensity in these organs on the T1 in-phase images compared to the T1 out-of-phase images. This is the opposite pattern to diffuse steatosis.

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Case information

rID: 69377
Published: 9th Jul 2019
Last edited: 14th Aug 2019
System: Haematology
Inclusion in quiz mode: Included

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