Silicosis with progressive massive fibrosis

Case contributed by Yaïr Glick
Diagnosis almost certain

Presentation

Hospitalized for intermittent fever. History of advanced silicosis. Lung transplant candidate.

Patient Data

Age: 50 years
Gender: Male

Severe apical fibrosis and diffuse reticulonodular pattern in both lungs.

  • mild supraclavicular lymphadenopathy (upper edge of scan).

  • non-enlarged elliptical axillary lymph nodes with no fatty hila

  • mediastinal lymphadenopathy in many stations, with subcarinal nodes reaching 17 mm (short axis)

  • bilateral hilar lymphadenopathy with delicate peripheral nodules of calcification

  • severe bilateral pulmonary fibrosis, particularly in the upper lobes. Innumerable perilymphatic nodules diffusely dispersed throughout the lungs

  • bilateral posteromedial pleural thickening

  • supradiaphragmatic lymphadenopathy, with nodes measuring up to 17 mm (short axis).

  • gastrohepatic ligament lymphadenopathy, with the largest mass/conglomerate measuring 39 mm across.

  • hypodense lesion in posteromedial aspect of the spleen measuring 30 x 23 x 30 mm, unchanged compared to previous scan (not shown) - probably a hemangioma.

  • the celiac trunk is severely stenotic at its origin.

Case Discussion

Typical features of progressive massive fibrosis on a background of pulmonary nodules and lymphadenopathy.

Occupational history is essential to the diagnosis.

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