Wilson disease - CNS manifestations

Case contributed by Dr Huda B. Gharbia

Presentation

Dysarthria, parkinsonism, gait disturbance.

Patient Data

Age: 16 years
Gender: Male

Bilateral symmetrical hypodensity in both basal ganglia (putamen), caudate nuclei, and ventrolateral thalami, Also noted hypodensity in midbrain, periaqueductal, posterior pons. There is a small calcification at the wall of the left lateral ventricle.

There are bilateral symmetrical hyperintensities on both T2W and FLAIR sequences in both lentiform nuclei (putamina), caudate nuclei, and ventrolateral aspect of both thalami.

Also noted hyperintensity in both T2W and FLAIR sequences in brainstem involving the midbrain and pons.

Case Discussion

Known case of Wilson disease with CNS manifestations, in the form of bilateral symmetrical hyperintensity of both basal ganglia and the brainstem.

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Case information

rID: 65738
Published: 21st Jan 2019
Last edited: 14th Aug 2019
Inclusion in quiz mode: Included

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