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Computed tomographic (CT) colonography

Computed tomographic (CT) colonography, also called CTC, virtual colonoscopy (VC) or CT pneumocolon, is a powerful minimally invasive technique for colorectal cancer screening. Indications screening test for colorectal carcinoma colon evaluation after incomplete or unsuccessful conventional c...

CT enteroclysis

Computed tomographic (CT) enteroclysis refers to a hybrid technique that combines the methods of fluoroscopic intubation-infusion small bowel examinations with that of abdominal CT 1. Indications CT enteroclysis is complementary to capsule endoscopy in the elective investigation of small-bowel...

Gastrointestinal MRI contrast agents

Gastrointestinal MRI contrast agents are varied and can be either positive or negative agents. Acceptance of the use of MRI in abdominal imaging has been limited in part by difficulty in distinguishing bowel from intra-abdominal masses and normal organs. The use of enteric contrast agents can ai...

Indium-111 OncoScint

Indium-111 OncoScint is a radiopharmaceutical used in SPECT imaging. It is a labeled monoclonal antibody that is directed against TAG-72, which is a tumor-associated antigen associated with ~95% of colorectal carcinomas and 100% of ovarian carcinomas 1,2. Background hepatic uptake limits sensiti...

Lanthanum therapy

Lanthanum therapy is used to treat hyperphosphatemia in end-stage renal disease 1. It is taken as oral tablets (usually in the chemical form Lanthanum carbonate) which dissociate in the acidic environment of the stomach. The released trivalent Lanthanum cation has a high affinity for dietary pho...

MR enterography

MR enterography is a non-invasive technique for diagnosis of small bowel disorders. Indications MR enterography is most commonly used to evaluate patients with Crohn disease where it is used for assessment of the primary disease and any complications. Other indications include celiac disease, ...

Octreotide scintigraphy

Octreotide scintigraphy uses 111In-labeled octreotide which is a somatostatin analog; it is also known as an OctreoscanTM, a brand name for 111In-labeled pentetreotide; pentetreotide is a DTPA-conjugated form of octreotide, originally manufactured by Mallinckrodt Nuclear Medicine LLC, which now ...

Portosystemic shunt ratio

The portosystemic shunt ratio is a measure performed using ultrasound to quantify the abnormal flow of portal venous blood that is shunted away from the hepatic sinusoidal circulation in the context of a congenital portosystemic shunt 1. Ultrasound The ratio is determined using the following e...

Rectal cancer protocol (MRI)

MRI protocol for rectal cancer is a group of MRI sequences put together for imaging staging of primary tumors of the rectum.  Note: This article is intended to outline some general principles of protocol design. The specifics will vary depending on MRI hardware and software, radiologist's and r...


SeHCAT™ (23-seleno-25-homo-tauro-cholic acid or tauroselcholic acid) is a radiopharmaceutical used in the investigation of bile salt malabsorption, which is a cause of chronic diarrhea.  Characteristics physical half-life: 118 days Uses, dosage and timings A capsule containing SeHCAT is inge...

Tc-99m labeled RBC

Tc-99m labeled RBC is one of the technetium radiopharmaceuticals used in the assessment of GI bleeding. Characteristics photon energy: 140 KeV physical half life: 6 hours biological half life:  normal distribution: heart, vessels, spleen miscellaneous facts: threshold for detection is 0.0...

Tc-99m pertechnetate

Tc-99m pertechnetate (Na+ 99mTc O4-) is one of the technetium radiopharmaceuticals used in imaging of thyroid, colon, bladder and stomach. Technetium (99mTc) has eight oxidation states 6, from -1 to +7; specifically, the oxidation state of technetium in the pertechnetate anion (99mTcO4-) is +7....

Tc-99m sulfur colloid

Technetium-99m sulfur colloid is one of the technetium radiopharmaceuticals. Characteristics photon energy: 140 keV physical half-life: 6 hours biological half-life normal distribution: liver: 85% spleen: 10% bone marrow: 5% excretion: hepatic target organ: liver, spleen pharmacokinet...

Twinkling artifact

Twinkling artifact is the result of intrinsic machine noise seen with color Doppler ultrasound 1. It occurs as a focus of alternating colors on Doppler signal behind a reflective object (such as calculi), which gives the appearance of turbulent blood flow 2. It appears with or without an associa...

Vicarious contrast material excretion

Vicarious contrast material excretion (VCME) defines excretion of water-soluble contrast material in a way other than via normal renal excretion.  The most common vicarious excretion of water-soluble contrast material is via the liver, resulting in increased bile density seen in the gallbladder...

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