Caudal regression syndrome

Discussion:

Caudal regression syndrome is characterized by: 

  • absence of vertebral column, usually below level of L1.

  • occurs as a result of notochordal cell apoptosis, not formed in their correct craniocaudal position. 

  • may be seen with:

    • OEIS (Omphalocele, Exstrophy, Imperforate anus, Spinal Defects)

    • VACTERL

    • Currarino Triad (Sacral agenesis, Anal atresia/ malformation, Presacral mass; Meningocele/ Teratoma)

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