Trousseau syndrome - gallbladder carcinoma presenting with bilateral lower limb migratory deep vein thrombosis and superficial thrombophlebitis

Discussion:

Migratory DVT and bilateral superficial thrombophlebitis of the left then right lower limbs were the early signs of a yet to be diagnosed gall bladder carcinoma with peritoneal carcinomatosis.

Trousseau syndrome is a cancer-induced hypercoagulable status with usually undiagnosed - or yet to be diagnosed - cancer that can present with migratory deep venous thrombosis and thrombophlebitis, acute cerebral infarction, or non-bacterial thrombotic endocarditis.

It must be suspected in elderly patients developing DVT or superficial thrombophlebitis with no definite underlying or predisposing factors. Transient and migratory DVT or superficial thrombophlebitis should prompt the work-up for underlying undiagnosed malignancy in these patients.

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