The patient went on to have the usual barrage of tests, confirming him to have high viral loads of JC virus, consistent with the diagnosis of PML.
- Polyomavirus DNA by PCR: DETECTED
- BK Viral Load:677,000 Copies/mL
- JC Viral Load: 4,367,500 Copies/mL
- CRYPTOCOCCAL SEROLOGY: Specimen type - Serum and CSF - Cryptococcal Ag: NOT Detected
- CSF MICROSCOPIC DESCRIPTION
- Lymphocytes 161
- The smears contain increased numbers of lymphocytes. No malignant cells are identified.
- HERPES VIRUS MULTIPLEX PCR: VIRUS DNA NOT DETECTED
- T-CELL SUBSETS
- Total WCC 30.50 x10^9/L (normal = 4.00-11.00)
- Total Lymph 0.30 x10^9/L (normal = 1.20-4.00)
- % CD3 32.90 %
- Total CD3 0.10 x10^9/L (normal = 0.70-3.58)
- % CD4 2.30 %
- Total CD4 0.01 x10^9/L (normal = 0.35-2.63)
- % CD8 28.80 %
- Total CD8 0.09 x10^9/L (normal = 0.12-1.47)
- CD4:CD8 0.08 1.00-2.40
- HIV VIRUS LOAD REPORT
- HIV-1 RNA by RT-PCR : DETECTED
- HIV-1 RNA Load : <150 RNA copies/mL plasm
- COMMENT: This result has been obtained using the Abbott Real Time HIV-1 Assay. This amplifies all Group M, N and O subtypes. The reliable limit of detection for the assay is 150-10,000,000 RNA copies/ml.