Sickle cell anemia

Discussion:

The patient had a history of sickle-cell anemia.

This is an early example of the classical H-shaped vertebrae seen in sickle-cell anemia. H-shaped vertebrae are a characteristic finding seen in ~10% of patients with the disease. Bone infarction may be complicated by Salmonella osteomyelitis. Other signs to look for on chest films are cardiomegaly, absent spleen, and cholecystectomy clips.

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