Langerhans cell histiocytosis

Discussion:

Langerhans cell histiocytosis (LCH) is a rare multi-system disease with a wide and heterogeneous clinical spectrum and variable extent of involvement.  The musculoskeletal system is the commonest site of presentation.

The vertebral plana and addition pelvic lesion in this case are consistent with the histology from the tibial bone biopsy.

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