Hepatocellular carcinoma containing microscopic (intracytoplasmic) fat

Discussion:

Histological diagnosis of HCC was confirmed. This is a unusual case of HCC containing microscopic fat (signal drop on opposition phase images). In cirrhotic patient, more than 80 % of microscopic fat containing lesions are malignant, most of which are HCCs.

The differential diagnosis of fat containing liver lesions includes :

Benign:

Malignant:

  • HCC
  • metastastic liposarcoma
  • primary liposarcoma
  • other fat containing liver metastases
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