The clinical picture, in this case, was consistent with progressive supranuclear palsy (PSP), and imaging was supportive of this diagnosis. Note, that the presence of left frontal lobe and insular atrophy also fits well as there is an overlap of PSP with non-fluent aphasia variant of frontotemporal dementia (nfvFTD) as both conditions are associated with accumulation of tau (see tauopathies).