Histopathology:
MACROSCOPIC DESCRIPTION:
"Left radial orchidectomy": An orchidectomy specimen with testis (103 g, 68 x 57 x 42 mm) and spermatic cord (53 mm length, up to 22 mm diameter). The tunica vaginalis is shiny smooth and mobile, inked black.
Replacing almost the entire testis is a homogeneous lobulated soft tan-pink tumour 64 x 54 x 40 mm. Tumour extensively abuts tunica albuginea but appears clear of tunica vaginalis. There is possible infiltration of rete however the epididymis appears clear of tumour. Adjacent to tumour there is a small rim of normal appearing testis parenchyma.
MICROSCOPIC DESCRIPTION:
The sections of testis show a tumour comprising sheets and nests of polygonal cells separated by fibrovascular septa containing lymphocytes. Tumour cells have abundant pale cytoplasm, large vesicular nuclei and prominent nucleoli. Other germ cell tumour components and syncytiotrophoblastic cells are not identified. Tumour focally infiltrates rete testis however does not invade epididymis. Tumour abuts but does not invade the tunica albuginea and is clear of tunica vaginalis. Definite lymphovascular invasion is not present. The spermatic cord margin is clear of tumour. Adjacent testis parenchyma shows intratubular germ cell neoplasia.
DIAGNOSIS: Seminoma.