Cytotoxic lesion of the corpus callosum (CLOCC)

Discussion:

This case illustrates typical appearances of a cytotoxic lesion of the corpus callosum (CLOCC) also known by a variety of other names including: transient lesions of the splenium of the corpus callosum, mild encephalitis/encephalopathy with a reversible isolated SCC lesion (MERS), reversible splenial lesions and reversible splenial lesion syndrome (RESLES). 

Regardless of the name, these represent non-ischemic lesions seen in a variety of causes (including intracranial hemorrhage) that completely resolve. 

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