Corpus callosum lymphoma


The pathologic diagnosis was lymphoma which is usually hyperdense on CT; helpful in differentiating it from other malignancies.

The main differential diagnosis for a corpus callosal mass includes:

  • lymphoma (PCNSL)
  • glioblastoma multiforme (butterfly glioma)
  • less frequently encountered
    • tumefactive demyelination
    • radiation necrosis
    • evolving hemorrhage / contusion / infarct

Lipoma of the corpus callosum very rarely occurs, but the diagnosis is usually straight-forward since there is an obvious fat density.