Herlyn–Werner–Wunderlich syndrome is considered to be a rare type of Mullerian duct anomaly, it is characterized by uterus didelphys with blind hemivagina and associated ipsilateral renal agenesis.

Herlyn–Werner–Wunderlich syndrome is also known obstructed hemivagina, and ipsilateral renal anomaly (OHVIRA). It usually presents after menarche, with progressive pelvic pain during menses secondary to hematocolpos, so early diagnosis can help early treatment, ensure quick relief from symptoms and preserve the fertility and so prevent the complications.