Malignant fibrous histiocytoma of the humerus

Discussion:

Malignant fibrous histiocytoma (MFH) has now been re-termed with a more meanful pathological identity as a pleomorphic undifferentiated sarcoma.

It is a soft tissue based tumor, which can occur anywhere in the body. Less than 5% are bone derived as in this case.

MFHs occur in adults (range 32-80; mean 59 years) with a slight male predilection with a M:F ratio of 1.2:1). Presentation is usually with an painless, enlarging palpable mass - as in this case. 

Core biopsy confirmed the diagnosis.   The prognosis, as is usual with all sarcomas, is poor.

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