CLINICAL NOTES:
Right mandibular radiolucency for investigation ?keratocyst. -> specimen is lining/wall of cyst.
MACROSCOPIC DESCRIPTION: "Right mandibular ramus cyst": An irregular strip of tan and dark red tissue 35x7x3mm. 6xTS. A1. (SK)
MICROSCOPIC DESCRIPTION: Sections show strips of cyst wall with fibrous stroma. The cyst is lined by stratified squamous epithelium 5-10 cells thick, with an undulating surface and a basal layer with palisading. There are scattered mitoses, however nuclear atypia is not seen. Several areas of ulceration with granulation tissue and acute inflammation are present. The stroma contains a scattered moderate infiltrate of lymphocytes, plasma cells and occasional eosinophils and neutrophils. No daughter cysts or features of ameloblastoma are seen. There is no evidence of dysplasia or malignancy.
DIAGNOSIS: Right mandibular ramus cyst: Keratocystic odontogenic tumour (KCOT).