Caudal regression syndrome

Discussion:

There are four types of sacral agenesis:

In type 1, partial unilateral agenesis is localized to the sacrum or coccyx. 

In type 2, there are partial but bilaterally symmetric defects in the sacrum. The iliac bones articulate with S1, and distal segments of the sacrum and coccyx fail to develop. 

In type 3, there is total sacral agenesis and the iliac bones articulate with the lowest available segment of the lumbar spine. 

In type 4, there is total sacral agenesis and the iliac bones are fused posteriorly along the midline.

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