Marked asymmetric atrophy of the anterior left temporal lobe as well as, to a somewhat lesser degree, the left frontal opercular region including the expected location of Broca's area. There is a profound loss of temporal white matter volume with enlargement of the temporal horn. Associated mild increased subcortical FLAIR signal. The rest of the brain, including the hippocampi, demonstrate involutional change, exaggerated for age, but to a much less marked degree.
No intra-cranial mass lesions, acute haemorrhages or collections. No acute or established infarcts. Mild bi-hemispheric chronic white matter ischaemic change. Small anterior falcine calcification.
Conclusion:
Findings are in keeping with the language variant of frontotemporal dementia (semantic variant).