Crystal induced arthropathy (CPPD)

Discussion:

Calcium pyrophosphate deposition disease (CPPD) is a type of crystal arthropathy which affects middle-aged and old populations. Clinical manifestation of this deposition disease rages from pseudogout syndrome to asymptomatic joint disease. The radiographic hallmark of CPPD is the presence of chondrocalcinosis and secondary osteoarthritic changes. 

This patient presented with a long history of severe polyarthritis involving his hands, feet, wrist and knees manifested with recurrent joint pain and swelling. The patient was investigated and his workup revealed that he has a form of crystal-induced arthropathy related to calcium pyrophosphate deposition disease (CPPD). 

Bare in mind that chondrocalcinosis related to CPPD deposition can be caused by hyperparathyroidism and hemochromatosis.

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