Low grade glioma with radiation necrosis

Discussion:

The de novo lesions were suspicious of anaplastic transformation, hence biopsy was taken and confirmed radiation necrosis. DWI allowed early detection of areas of abnormal diffusion few months before the changes were detected on conventional MRI.

Note: IDH mutation status is not provided in this case and according to the current (2016) WHO classification of CNS tumors, this tumor would, therefore, be designated as a diffuse astrocytoma NOS.

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