MACROSCOPIC DESCRIPTION: "Left posterior mediastinal mass":

Piece of tissue, 50g, 60x45x40mm with one surface covered by a shiny fibrous membrane and other surface roughened (inked blue). Sectioning reveals a multilobulated well circumscribed tumour with heterogenous areas of solid growth, haemorrhage, friable necrosis and calcification. The tumour abuts the inked margin.

 MICROSCOPIC DESCRIPTION: Sections show a well-circumscribed, partly encapsulated, paucicellular tumour containing thick walled hyalinised vessels, areas of haemorrhage and dystrophic calcification. Tumour cells show mild nuclear atypia with focal Verocay body formation. Tumour cells stain S-100 positive, whilst they are negative for Neu-N, NFP and CD34. Histological and immunohistochemical features are those of an ancient schwannoma.

DIAGNOSIS: Left posterior mediastinal mass - Schwannoma, with ancient features.

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