Glioblastoma NOS

Discussion:

The patient went on to have a resection which confirmed the diagnosis of glioblastoma.

Histology

  • Neoplastic cells positive for GFAP (polyclonal)
  • Negative for EMA
  • Strong nuclear staining for P53 (D0-7)
  • Ki-67 positive in 15%

Note: IDH mutation status is not provided in this case and according to the current (2016) WHO classification of CNS tumors, this tumor would, therefore, be designated as a glioblastoma NOS.

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