The sections of temporal neocortex and white matter show foci of dyslamination in the middle temporal gyrus associated with fusion of contiguous molecular layers giving the appearances of localized polymicrogyria. Moderate numbers of large neurones are also noted in lamina I and there is disorientation of neurones within the middle laminae of the cortex. No balloon neurones are identified. Moderate numbers of mature neurones are seen in white matter. Myelination appears normal and there are no features of tumour. The features are of malformation of cortical development. The surgical margins are clear of the area of cortical dysplasia.
NeuN = neuronal nuclear antigen
Histology courtesy of Michael Gonzales, Royal Melbourne Hospital.