Lipoma of the colon is a rare benign tumor slow growth of mesenchymal origin usually diagnosed accidentally. The most frequent localization is in the right colon.

It is rarely symptomatic, and symptoms are usually related to the size of the lesion.

Those with more than 2 cm in diameter can cause abdominal pain, change in the hive, bleeding, obstruction or intussusception. Endoscopically they are presented as spherical polyps, smooth, often sessile, yellowish and covered with normal mucous. Rarely they are covered by ulcerated/necrotic mucosa and mimic a malignant tumor.

Case courtesy: Prof Fabio Denicolò