Marked basal ganglia atrophy, particularly of the caudate heads. Mild global supratentorial parenchymal volume loss is also evident, disproportionate for age. Mesial temporal structures maintain normal volume for age. No infratentorial atrophy.
NB: frontal horn-to-intercaudate (FH:CC) ratio and intercaudate-to-inner table (CC:IT) ratios are both abnormal.
Minor bright FLAIR signal seen in occipital white matter in a symmetrical fashion is of unclear significance. Few scattered nonspecific gliotic foci seen in centrum semiovale.
No area of diffusion restriction or intracranial haemorrhage.
Comment: Features typical of Huntington disease.