Neurofibromatosis type 1 - with optic pathway glioma
Optic pathway glioma has 3 broad types:
-Childhood benign tumors associated with NF1.
-Childhood benign tumors not associated with NF1.
-Adult tumors that are typically malignant.
Imaging findings:
-Best diagnostic tool: Fusiform optic nerve mass with variable posterior pathway involvement.
-Ranges from no enhancement to intense homogenous enhancement.
-Calcification is rare (unlike optic sheath meningioma).
-Bilateral intraorbital lesions indicate NF1.
-Associated neuroimaging findings if NF1 is present: Brain T2 foci, other CNS tumors, sphenoid dysplasia.