Fibrolamellar hepatocellular carcinoma is a distinct variant of generic hepatocellular carcinoma.

The 5 distinct aspects compared to generic HCC are:

• young age at presentation -  young adults (15 to 40 years of age)
• no association with cirrhosis
• usually large at presentation
• not associated with raises serum alpha feto protein
• less aggressive with a better 5-year survival

On cross sectional imaging the tumor is usually large, heterogeneous, enhances most in the arterial phase and may have a central 'scar' like component.