Items tagged “contrast_agents”
12 results found
Thorotrast is a suspension of radioactive thorium dioxide first produced in Germany in 1928 and used as a contrast agent until the 1950s. Its principal use was for cerebral angiography: 90% of the estimated 50,000-100,000 patients treated received it for this purpose. Basic principles Thorotra...
Myoinositol is one of the compounds images with MR spectroscopy (MRS) at both 1.5 T and 3 T and is seen to resonate at 3.5 ppm chemical shift (right of the choline peak). Myoinositol is a precursor of both phosphatidylinositol (the major inositol-containing phospholipid) and of phosphatidylino...
Published 22 Sep 2011
MRI contrast agents
MRI contrast agents have become an indispensable part of contemporary magnetic resonance imaging. Although MRI was initially hoped to provide a means of making definitive diagnoses without administering contrast media, it has been found that the addition of contrast agents in many cases improves...
Intravascular (blood pool) MRI contrast agents
Intravascular MRI contrast agents normally remain confined to the intravascular space, compared to Gd-DTPA which distributes throughout the extracellular fluid space. This is a result of intravascular agents having a molecular weight of approximately 70,000 and above, compared to a molecular wei...
Gd-DTPA labeled albumin
Gd-DTPA labeled albumin is an intravascular MRI contrast agent. Gd-DTPA is covalently bonded to albumin in ratios from 16:1 to 31:1 providing excellent enhancement of liver, spleen, myocardium, brain, and slow moving blood of rats and rabbits. The albumin has a molecular weight of about 92,000 a...
Gd-DTPA labeled dextran
Gd-DTPA labeled dextran is an intravascular MRI contrast agent. Dextran is a polysaccharide consisting of a polymer of glucose molecules with a molecular weight between 75,000-100,000. Dextran has a high level of safety and is broken down more rapidly than albumin. Approximately 15 Gd-DTPA molec...
Chromium-labeled red blood cells
Chromium-labeled red blood cells is an intravascular MRI contrast agent. The use of 51Cr-labeled RBCs in nuclear medicine suggested the use of paramagnetic Cr(III)-labeled RBCs as an intravascular contrast agent for MRI. In dogs, significant enhancement of the liver and spleen is noted with mini...
Meglumine iotroxate (Biliscopin)
Meglumine iotroxate (BiliscopinTM) is an iodinated, intravenous contrast agent that is preferentially excreted into the biliary tree and is used in CT intravenous cholangiography. The typical dose is 100 mL Biliscopin (105 mg meglumine iotroxate/mL; 5.0 g iodine), which is administered via slow...
Vicarious contrast material excretion
Published 07 Jan 2017
Barium sulfate (BaSO4), often just called barium in radiology parlance, is a salt of barium (Ba), a metallic chemical element with atomic number 56. Barium is considered one of the heavy metals. Unlike barium and many of its other salts, barium sulfate is insoluble in water and therefore very li...
Lipiodol® (also known as ethiodized oil) is an oil-based iodinated contrast medium that was historically used for myelography and hysterosalpingography. It was later superseded by newer, less hazardous, agents, and now is used primarily as a therapeutic agent. Guerbet is now the sole manufacture...