Items tagged “contrast_agents”

11 results found
Article

Thorotrast

Thorotrast was the trade name of a radioactive thorium dioxide suspension radiographic contrast media widely used between the 1930s and 1940s. It was popular for its use as an intravascular contrast agent, particularly for cerebral angiography. An estimated 2-10 million people are thought to hav...
Article

Myo-inositol peak

Myo-inositol is one of the compounds images with MR spectroscopy (MRS) at both 1.5 T and 3 T and is seen to resonate at 3.5 ppm chemical shift (right of the choline peak).  Myo-inositol is a precursor of both phosphatidylinositol (the major inositol-containing phospholipid) and phosphatidylinos...
Article

MRI contrast agents

MRI contrast agents have become an indispensable part of contemporary magnetic resonance imaging. Although MRI was initially hoped to provide a means of making definitive diagnoses without administering contrast media, it has been found that the addition of contrast agents in many cases improves...
Article

Intravascular (blood pool) MRI contrast agents

Intravascular MRI contrast agents normally remain confined to the intravascular space, compared to Gd-DTPA which distributes throughout the extracellular fluid space. This is a result of intravascular agents having a molecular weight of approximately 70,000 and above, compared to a molecular wei...
Article

Gd-DTPA labeled albumin

Gd-DTPA labeled albumin is an intravascular MRI contrast agent. Gd-DTPA is covalently bonded to albumin in ratios from 16:1 to 31:1 providing excellent enhancement of liver, spleen, myocardium, brain, and slow moving blood of rats and rabbits. The albumin has a molecular weight of about 92,000 a...
Article

Gd-DTPA labeled dextran

Gd-DTPA labeled dextran is an intravascular MRI contrast agent. Dextran is a polysaccharide consisting of a polymer of glucose molecules with a molecular weight between 75,000-100,000. Dextran has a high level of safety and is broken down more rapidly than albumin. Approximately 15 Gd-DTPA molec...
Article

Chromium-labeled red blood cells

Chromium-labeled red blood cells is an intravascular MRI contrast agent. The use of 51Cr-labeled RBCs in nuclear medicine suggested the use of paramagnetic Cr(III)-labeled RBCs as an intravascular contrast agent for MRI. In dogs, significant enhancement of the liver and spleen is noted with mini...
Article

Meglumine iotroxate (Biliscopin)

Meglumine iotroxate (BiliscopinTM) is an iodinated, intravenous contrast agent that is preferentially excreted into the biliary tree and is used in CT intravenous cholangiography. The typical dose is 100 mL Biliscopin (105 mg meglumine iotroxate/mL; 5.0 g iodine), which is administered via slow...
Article

Lipiodol

Lipiodol (also known as ethiodized oil) is an oil-based iodinated contrast medium that was historically used for myelography and hysterosalpingography 1. It was later superseded by newer, less hazardous, agents, and now is used primarily as a therapeutic agent. Guerbet is now the sole manufactur...
Article

Prolonged heterogeneous liver enhancement (CEUS)

Prolonged heterogeneous liver enhancement (PHLE), also informally termed as the "disappearing liver" phenomenon, is a very rare, benign complication of ultrasound contrast media, of currently unknown etiology 1. PHLE manifests itself as confluent, rapidly appearing hyperechoic foci in the liver,...
Article

Levovist

Levovist (Bayer AG) is a first-generation ultrasound contrast agent composed of a microbubble solution filled with a gas that is easily visible on ultrasound scans 1,2. Levovist is commonly used as an ultrasound contrast agent in imaging the liver. The microbubbles in Levovist contain perflubut...

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