Items tagged “immunology”

7 results found
Article

IgG4-related disease

IgG4-related disease (IgG4-RD) is a systemic disease that is characterized by fibroinflammatory infiltration of various organs induced by plasma cells that express IgG4 (immunoglobulin G subclass 4). Terminology Since 2012, IgG4-related disease has become the preferred term 9,10. However, it h...
Article

Systemic lupus erythematosus

Systemic lupus erythematosus (SLE) is a complex autoimmune disease with multisystem involvement. Although abnormalities in almost every aspect of the immune system have been found, the key defect is thought to result from a loss of self-tolerance to autoantigens. Epidemiology There is a strong...
Article

IgG4-related lung disease

IgG4-related lung disease is a recently described condition. It may occur with or without systemic involvement. It is considered part of the spectrum of IgG4-related disease. Radiographic features CT On HRCT of the chest, it may be categorized into four major subtypes 5: solid nodular subtyp...
Article

Hyperimmunoglobulin IgE syndrome

Hyperimmunoglobulin E (hyper IgE) syndrome (HIES), also known as Job syndrome, consists of a heterogeneous group of complex hereditary combined B- and T-cell immune deficiency diseases characterized by recurrent Staphylococcus aureus chest infections, characteristic coarse facial appearance and ...
Article

IgG4-related hypophysitis

IgG4-related hypophysitis is a rare cause of inflammation of the pituitary gland and an uncommon manifestation of the systemic IgG4-related disease (IgG4-RD). Epidemiology Although IgG4-RD tends to present in middle-aged and elderly men, the gender ratio is more balanced in patients with IgG4-...
Article

Systemic lupus erythematosus (CNS manifestations)

Central nervous system manifestations of systemic lupus erythematosus (CNS lupus), also known as neuropsychiatric systemic lupus erythematosus (NPSLE), describe a very diverse range of neuropsychiatric manifestations that are secondary to systemic lupus erythematosus (SLE) in the central nervous...
Article

Lymphoma response to immunomodulatory therapy criteria (LYRIC)

The Lymphoma Response to Immunomodulatory Therapy Criteria (LYRIC) represents an adaptation of the Lugano classification for the evaluation of lymphoma after immune-based treatment. During immunomodulatory agents (e.g. checkpoint inhibitors) therapy, imaging findings suggestive of progressive d...

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