Items tagged “lymphoma”
19 results found
Article
Breast lymphoma
Breast lymphoma refers to the involvement of the breast with lymphoma and may be primary or secondary.
Epidemiology
Both primary and secondary breast lymphomas are rare. Breast lymphoma accounts for <1% of all breast malignancies and <2% of all extranodal non-Hodgkin lymphoma 11. Secondary lym...
Article
Lymphomas of the central nervous system
Lymphomas of the central nervous system, the most common of which is primary diffuse large B-cell lymphoma of the CNS, are the second most common primary brain tumor after gliomas 17. By definition, there is no co-existing systemic disease at the time of diagnosis, distinguishing it from CNS inv...
Article
Gastric lymphoma
Gastric lymphoma may either represent secondary involvement by systemic disease or primary malignancy confined to the stomach.
Epidemiology
Gastric lymphoma represents the most common site of extranodal lymphoma, accounting for 25% of all such lymphomas, 50% of all gastrointestinal lymphomas...
Article
Hodgkin lymphoma
Hodgkin lymphoma or Hodgkin disease (HD) is a type of lymphoma and accounts for ~1% of all cancers. Hodgkin disease spreads contiguously and predictably along lymphatic pathways and is curable in ~90% of cases, depending on its stage and subtype.
Epidemiology
There is a bimodal distribution in...
Article
Primary hepatic lymphoma
Primary hepatic lymphoma (PHL) is very rare, with approximately 100 described cases. If it is being considered as a diagnosis, distant lymphadenopathy, splenomegaly, bone marrow disease, and leukemia should not be present for at least 6 months after the liver tumor has been detected (see: second...
Article
Lymphoma
Lymphoma (historically lymphosarcoma was used for diffuse forms of the disease) is a malignancy arising from lymphocytes or lymphoblasts. Lymphoma can be restricted to the lymphatic system or can arise as extranodal disease. This, along with variable aggressiveness results in a diverse imaging a...
Article
Mediastinal lymphoma
Mediastinal lymphoma is common, either as part of disseminated disease or less commonly as the site of primary involvement.
Epidemiology
Lymphomas are responsible for approximately 15% of all primary mediastinal masses, and 45% of anterior mediastinal masses in children 1.
Only 10% of lympho...
Article
WHO classification of haematolymphoid tumors
The World Health Organization (WHO) classification of haematolymphoid tumors is the most widely used pathologic classification system for hematopoietic and lymphoid neoplasms. The current revision 1, known as the 5th edition, was published in 2022 and supersedes the 4th edition revised published...
Article
Orbital lymphoma
Primary lymphoma of the orbit is one of the most common orbital tumors and accounts for as much as half of all orbital malignancies. It is a B-cell non-Hodgkin lymphoma, and in most cases arises from mucosa-associated lymphoid tissue (MALT).
Epidemiology
Orbital lymphomas account for only 2% o...
Article
CNS lymphoma
CNS lymphoma refers to the involvement of the central nervous system with lymphoma. It can be broadly divided into primary and secondary, with a number of special types also recognized.
primary lymphomas of the CNS
primary diffuse large B-cell lymphoma of the CNS
immunodeficiency-associated ...
Article
Follicular lymphoma
Follicular lymphoma is the most common subtype of indolent non-Hodgkin lymphoma (NHL), second most common overall, behind diffuse large B-cell lymphoma 6.
Epidemiology
Estimated to account for ~45% of all NHL cases 1. Higher rates in North America and Europe 4.
Pathology
Nodal effacement b...
Article
Floating aorta sign
The floating aorta sign refers to displacing the abdominal aorta away from the vertebral column.
It is a radiographic sign of retroperitoneal masses and most commonly suggests a lymphoma diagnosis. Rarely, other diseases with diffuse retroperitoneal mass, such as Castleman's disease, primary re...
Article
Mycosis fungoides
Mycosis fungoides (MF) is a type of malignant cutaneous primary T-cell lymphoma.
Epidemiology
In the United States, it is more common in males and African Americans. In Europe, it accounts for ~6% of all non-Hodgkin lymphomas. It is rare in Asian countries.
Clinical presentation
It is usual...
Article
Pituitary lymphoma
Pituitary lymphoma is very rare, although lymphomatous (or leukemic) infiltration of the perisellar dura is not infrequently encountered as part of more widespread CNS disease. This article concerns itself with involvement of the pituitary itself rather than the region more broadly. For a genera...
Article
Deauville five-point scale
The Deauville five-point scale (Deauville 5PS) is an internationally-recommended scale for routine clinical reporting and clinical trials using FDG PET-CT in the initial staging and assessment of treatment response in Hodgkin lymphoma (HL) and certain types of non-Hodgkin lymphomas (NHL).
Incl...
Article
Gastrointestinal nodular lymphoid hyperplasia
Gastrointestinal nodular lymphoid hyperplasia is a type of nodular lymphoid hyperplasia that can be found elsewhere in the body. It is formed out of gut-associated lymphoid tissue (GALT), and most often is a diagnostic dilemma for radiologists in the stomach and terminal ileum.
Pathology
Gut-a...
Article
Lymphoma response to immunomodulatory therapy criteria (LYRIC)
The Lymphoma Response to Immunomodulatory Therapy Criteria (LYRIC) represents an adaptation of the Lugano classification for the evaluation of lymphoma after immune-based treatment.
During immunomodulatory agents (e.g. checkpoint inhibitors) therapy, imaging findings suggestive of progressive d...
Article
Helicobacter pylori
Helicobacter pylori (H. pylori) is a gram-negative spiral flagellate microaerophilic bacterium found in the human gastric mucosa 1. It is classified as a Group I carcinogen and is considered necessary but insufficient alone to cause gastric adenocarcinoma. More often than not, it results in chro...
Article
Yttrium-90 ibritumomab tiuxetan
Yttrium-90 ibritumomab tiuxetan, also known by the trade name Zevalin (Acrotech Biopharma LLC, USA), is a theranostic radiopharmaceutical approved for the treatment of patients with relapsed or refractory low grade or follicular non-Hodgkin lymphoma (NHL). More specifically, it is a radioimmunot...
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