Items tagged “soft tissue sarcoma”

10 results found
Article

Alveolar soft part sarcoma

Alveolar soft part sarcoma (ASPS) is a rare, highly vascular, deep soft tissue mesenchymal malignancy that is classically seen in the lower extremities of young adults. They account for <1% of all soft tissue sarcomas. Epidemiology There is a slight female predilection in patients less than 30...
Article

Dedifferentiated liposarcoma

Dedifferentiated liposarcomas (DDLPS) are malignant adipocytic soft tissue neoplasms that have progressed from primary or recurrent atypical lipomatous tumors/well-differentiated liposarcomas and are characterized by a much higher rate of recurrence, metastasis in about one-fourth of the cases a...
Article

Pleomorphic liposarcoma

Pleomorphic liposarcomas are high-grade malignant neoplasms arising from adipocytic tissues characterized by a variable number of pleomorphic lipoblasts and the absence of areas of well-differentiated liposarcoma and other lines of differentiation. Epidemiology Pleomorphic sarcomas are rare an...
Article

Myxoid pleomorphic liposarcoma

Myxoid pleomorphic liposarcomas are extremely rare aggressive malignant neoplasms arising from adipocytic tissues characterized by a mixture of pleomorphic and myxoid features and the absence of genetic fusions and amplifications seen in well-differentiated liposarcoma and other lines of differe...
Article

Adult fibrosarcoma

Adult fibrosarcomas are rare, malignant and highly aggressive fibroblastic soft tissue tumors. They constitute a diagnosis of exclusion. Epidemiology Adult fibrosarcomas by more recent definition are rare and make up around 1% of soft tissue sarcomas. They are mostly seen in middle-aged people...
Article

Infantile fibrosarcoma

Infantile fibrosarcomas also known as congenital fibrosarcoma, infantile fibrosarcoma-like tumor, and cellular congenital mesoblastic nephroma are locally aggressive rarely metastasizing fibroblastic tumors found in the pediatric population. Epidemiology Infantile fibrosarcomas are most common...
Article

Low-grade myofibroblastic sarcoma

Low-grade myofibroblastic sarcomas, also known as myofibrosarcoma are locally aggressive rarely metastasizing fibroblastic tumors. Epidemiology Low-grade myofibroblastic sarcomas most commonly occur in adults in the 4th and 5th decade of life with a minor male predominance and are rarely found...
Article

Low-grade fibromyxoid sarcoma

Low-grade fibromyxoid sarcomas also known as Evans tumors are malignant fibroblastic soft tissue neoplasms characterized by alternating fibrous and myxoid elements and a propensity to late recurrence and metastasis. Terminology The term hyalinizing spindle cell tumor with giant rosettes is now...
Article

Sclerosing epithelioid fibrosarcoma

Sclerosing epithelioid fibrosarcomas are rare slow-growing malignant fibroblastic soft tissue neoplasms pictured by a dense sclerotic hyalinized stroma with cords and areas of epithelioid fibroblasts. Epidemiology The tumor is rare and usually found in the middle-aged and elderly population. T...
Article

Inflammatory leiomyosarcoma

Inflammatory leiomyosarcomas are malignant tumors with smooth muscle differentiation and a prominent inflammatory infiltrate that were just recently recognized as a distinct entity by the WHO in 2020 1-3. Epidemiology Inflammatory leiomyosarcomas are very rare lesions with most cases seen in a...

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