Sinonasal lymphoma
Updates to Article Attributes
Sinonasal lymphoma refers to the involvement of the nasal cavity and/or paranasal sinuses with lymphoma. It can be primary or secondary.
Clinical presentation
The most common locations of the sinonasal lymphoma are the nasal cavity and the maxillary sinus. Generally, T-cell lymphoma (especially nasal T/NK-cell lymphoma), commonly seen in the Asian and South American populations, most frequently involves the nasal cavity whereas the B-cell lymphoma commonly seen in the Western populations, usually involves the paranasal sinuses 5.
Presenting symptoms of sinonasal lymphoma are variable but are usually similar to those of benign inflammatory diseases. The clinical symptom spectrum includes nasal obstruction, rhinorrhea, bloody discharge/epistaxis/epistaxis, postnasal drip, facial swelling, neck mass, orbital symptoms, fever, and body weight loss.
Pathology
It can be represented by various cytological types but the most common forms to arise in the sinonasal area is thought to be DLBCL (diffuse large cell B cell lymphoma), followed by nasal NK/T-cell lymphoma 3. There is a predilection for the nasal cavities involvement over the paranasal sinuses.
Radiographic features
Sinonasal lymphomas may be either seen as diffusely infiltrating lesions extending along walls of paranasal sinuses and nasal cavity or as discrete sinonasal soft tissue mass-like lesions.
CT
Soft tissue attenuating regions, either isoattenuating to the muscles or hyperattenuating due to a high nucleocytoplasmic ratio. CT is good at assessing associated bone destruction.
MRI
MRI is considered the optimal imaging modality for assessing locoregional extent of disease:
- T1: lesions appear as intermediate signal pattern
- T2/STIR: hypointense
- T1 C+: contrast enhancement of lymphomas is variable, usually tends to be homogeneous in pretreatment lymphomas
Differential diagnosis
- sinonasal granulomatosis with polyangiitis
-
sinonasal carcinoma
- adenocarcinoma
- squamous cell carcinoma (SCC)
-
esthesioneuroblastoma
- superior portions of the nasal cavity, near the cribriform plate
- sinonasal melanoma
-<p><strong>Sinonasal lymphoma</strong> refers to the involvement of the nasal cavity and/or paranasal sinuses with <a href="/articles/lymphoma">lymphoma</a>. It can be primary or secondary.</p><h4>Clinical presentation</h4><p>The most common locations of the sinonasal lymphoma are the nasal cavity and the maxillary sinus. Generally, T-cell lymphoma (especially nasal T/NK-cell lymphoma), commonly seen in the Asian and South American populations, most frequently involves the nasal cavity whereas the B-cell lymphoma commonly seen in the Western populations, usually involves the paranasal sinuses <sup>5</sup>.</p><p>Presenting symptoms of sinonasal lymphoma are variable but are usually similar to those of benign inflammatory diseases. The clinical symptom spectrum includes nasal obstruction, rhinorrhea, bloody discharge/epistaxis, postnasal drip, facial swelling, neck mass, orbital symptoms, fever, and body weight loss.</p><h4>Pathology</h4><p>It can be represented by various cytological types but the most common forms to arise in the sinonasal area is thought to be DLBCL (diffuse large cell B cell lymphoma), followed by nasal NK/T-cell lymphoma <sup>3</sup>. There is a predilection for the nasal cavities involvement over the paranasal sinuses. </p><h4>Radiographic features</h4><p>Sinonasal lymphomas may be either seen as diffusely infiltrating lesions extending along walls of paranasal sinuses and nasal cavity or as discrete sinonasal soft tissue mass-like lesions.</p><h5>CT</h5><p>Soft tissue attenuating regions, either isoattenuating to the muscles or hyperattenuating due to a high nucleocytoplasmic ratio. CT is good at assessing associated bone destruction.</p><h5>MRI</h5><p>MRI is considered the optimal imaging modality for assessing locoregional extent of disease:</p><ul>- +<p><strong>Sinonasal lymphoma</strong> refers to the involvement of the nasal cavity and/or paranasal sinuses with <a href="/articles/lymphoma">lymphoma</a>. It can be primary or secondary.</p><h4>Clinical presentation</h4><p>The most common locations of sinonasal lymphoma are the nasal cavity and the maxillary sinus. Generally, T-cell lymphoma (especially nasal T/NK-cell lymphoma), commonly seen in the Asian and South American populations, most frequently involves the nasal cavity whereas the B-cell lymphoma commonly seen in the Western populations, usually involves the paranasal sinuses <sup>5</sup>.</p><p>Presenting symptoms of sinonasal lymphoma are variable but are usually similar to those of benign inflammatory diseases. The clinical symptom spectrum includes nasal obstruction, rhinorrhea, bloody discharge/<a title="Epistaxis" href="/articles/epistaxis">epistaxis</a>, postnasal drip, facial swelling, neck mass, orbital symptoms, <a title="Fever" href="/articles/pyrexia">fever</a>, and <a title="Weight loss" href="/articles/weight-loss">weight loss</a>.</p><h4>Pathology</h4><p>It can be represented by various cytological types but the most common forms to arise in the sinonasal area is thought to be DLBCL (diffuse large cell B cell lymphoma), followed by nasal NK/T-cell lymphoma <sup>3</sup>. There is a predilection for the nasal cavities involvement over the paranasal sinuses. </p><h4>Radiographic features</h4><p>Sinonasal lymphomas may be either seen as diffusely infiltrating lesions extending along walls of paranasal sinuses and nasal cavity or as discrete sinonasal soft tissue mass-like lesions.</p><h5>CT</h5><p>Soft tissue attenuating regions, either isoattenuating to the muscles or hyperattenuating due to a high nucleocytoplasmic ratio. CT is good at assessing associated bone destruction.</p><h5>MRI</h5><p>MRI is considered the optimal imaging modality for assessing locoregional extent of disease:</p><ul>
-<a title="sinonasal carcinoma" href="/articles/sinonasal-carcinoma">sinonasal carcinoma</a><ul>- +<a href="/articles/sinonasal-carcinoma">sinonasal carcinoma</a><ul>
Unable to process the form. Check for errors and try again.