A 2.5 cm extra-axial, apparently simple cyst is seen to the right of the anterior falx, displacing the adjacent superior frontal gyrus. Arising from the cortex of the displaced gyrus, however, is a non-enhancing, very high T2 partially FLAIR suppressing nodule, with its medial margin outlined by a rim of high FLAIR signal. How it relates to the cys" is unclear. The nodule demonstrates no calcification or no contrast enhancement. ADC values are facilitated (2000 x 10^-6 mm^2/s).
The remainder of the brain is unremarkable in appearance.
Conclusion:
A non-enhancing high T2 cortical exophytic nodule from the right superior frontal gyrus is related to the known 2.5 cm parafalcine cyst. The appearance of the cortical lesion most closely resembles a dysembryoplastic neuroepithelial tumour (DNET). Although this is not a common association with Li Fraumeni syndrome, it is reported. Other lesions with mural nodules (e.g. pilocytic astrocytoma or pleomorphic xanthastrocytomas) would be expected to demonstrate vivid contrast enhancement.